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DISEASES THAT LEAD TO KIDNEY FAILURE


(1) DIABETES MELLITUS
Patients suffering from diabetes mellitus are prone to kidney diseases. If the diabetes continues uncontrolled and suffering continues for more than 15 years all the parts of the kidney are affected. Adequate control of hyper tension and diabetes will help retarding
the rate of renal diseases.

(2) ARTHIRITIS

In certain cases of Rheumatoid arthiritis the glomerular function of the kidneys are affected. Antirheumatoid drugs also may damage the kidney function.

(3) SYSTEMIC LUPUS ERYTHEMATIOSUS

It is one of the collagen diseases. Red patches form on the skin and spread through out the body the disease affects the renal function and lead to nephrotic syndrom, acute and chronic renal failures.

(4) TUBERCULOSIS OF THE KIDNEY
If kidney is affected by tuberculosis and not contained it will lead. to advanced state and the desfunction of the kidneys.

(5) POLYARTENITIS NUDOSA

It is a collagen disease where the walls of the arteries in various parts of the body become inflamed leading to asthma, high blood pressure and kidney failure.

(6) GOUT
In cases of gout when there is a massive increase of plasma uric acid may lead to malfunction of kidneys. Chronic gout patients are prone to renal failure.

(7) BACTERIAL INFECTION OF THE HEART VALVES
Persistent infection of the heart valves by streptococus and strephylococcus bacterias may develope immune complex in glomeroli. which will lead to glomerulo nephritis, nephrotic syndrome and acute nephrotic syndrome.

(8) NEPHROLITHIASIS:(KIDNEY STONE)
It is the presence of stones (Calculi) in the kidneys or urinary passage. It is characterised by renal pain and blood in urine. The presence of stones can be seen by taking X ray of theabdomen.

(9) RENAL TUBULAR DEFECTS

Functional disorders of the renal tubules by the presence of cysts etc.

(10) URINARY TRACT INFECTIONS THAT LEAP TO KIDNEY DISEASES

Urinary tract is a formal site to bacterial infection. Women are more prone urinary
infection some time or other in their lives. Some of the Infections affect the kidneys.


(11) ACUTE PYELONEPHRITIS

It is the acute Inflammation of the kidney and its pelvis. Fever chills, back pain are the symptoms. The abdominal pain will resemble the pain that occurs during appendicitis. Hypertension and shock may develope in children, fever, vomiting, abdominal pain and tenderness nocturnal enuresis or failure to grow normally are the symptoms. Urine will be turbid and blood stained. Urine test will show pus cells, erythrocytes, leukocyte casts and bacteria. Proteinuria may also be present. In severe cases renal failure may occur.

(12) CHRONIC PYELONEPHRITIS
Frequent and persistent urinary infection will lead to chronic Pyelonephritis. It leads to
impairment of renal function, polyurea, nocturia, hypertension, bone pains and symptoms of uraemia.


(13) CYSTITIS
If there urinary infection is limited to bladder it is called Cystitis. Acute bacterial
cystits leads to frequency of urine, urgency, dysuria, nocturia public discomfort
and low back pain fever & chills may be present. Haematuria, Pyuria and bacteriurea may also be present.

(14)URINARY ABNORMALITIES
If there is significant proteinurea ranging from 150mg to 3.5g/day) haematuria and pyurea
occurs with that any other symptoms, such person should go for proper investigation to see their renal functions are affected.

COMMON URINARY SYMPTOMS
The following urinary symptoms indicate the disease of urinary tract, bladder, urethera
which ultimately lead to the disease of the kidneys. As soon as the symptoms appear proper medical care should be sought to avoid the damage of kidneys.

(15) DYSURIA
Difficult and painful urination. This is called dysuria. It may be due to infection of urinary
tract, stones, foreign bodies, or new growth of bladder or urethera.


(16) URGENCY TO PASS URINE

Sudden and uncontrollable urgency to pass urine and some time urine is passed
involuntarily. Inflammation of bladder and urethera may be the reasons of this.


(17) PAINFUL URINATION
A painful desire to pass urine even when the bladder is empty. This may be due to urinary infections.

(18) PASSING URINE FREQUENTLY
The desire to pass urine more frequently. Normally the bladder can hold up to 500 ml of urine and a person pass urine once on 4 or 5 hours a day and the need not wake up during his sleep for urination. The frequency of urination shows that the bladder capacity is reduced because of inflammatory lesions, tumour, over stimulation or obstruction. In such condition quantity of urine in each voiding is reduced. In cold climates people may pass more frequently than other times. This should not be mistaken for the disease.

(19) INABILITY TO PASS URINE
Inability to pass urine which is collected in the bladder. This is due to the block to the urethera or nervous diseases. The common reasons are the blockage due to enlarged prostate, vesical and uretheral stones or bladder tumours.

(20) LEAKAGE OF URINE
The leakage of urine because the bladder cannot retain any amount of urine. This is because the ring muscles of urethera are damaged or paralysed.

(21) DRIBBING OF URINE
Dribbing of urine which occurs when the bladder is filled beyond the capacity. Some times even the abdominal pressure caused by coughing, sneezing, over-laughter may also result in dribbing.

(22) PASSING URINE DURING SLEEP
Unintentional voiding of urine during sleep is called enuresis. This is common with small children. If it happens with older age groups it may be due to under development of bladder control or loss of control because of obstruction or infection or nervous dysfunction.

(23) DAILY OUTPUT OF URINE
The daily output of urine in a normal person varies from 500 ml to 2500 ml depending on the fluid intake and climatic conditions. Two third of the total urine pass during the day and one-third during the night . Change of the usual volume of urine may be an indication of the renal disease.

(24) LOW OUTPUT OF URINE

If the volume of urine in a day is reduced below 400 ml it is called oliguria and if it is less than 100 ml it is anuria. some times total anuria also occurs. Both oliguria and anaemii are indications of shock, congestive cardiac failure, glomerulo nephritis and early stages of renal failure. Some times mechanical obstruction to the urinary passage also produces these Symptoms.

(25) HIGH OUTPUT OF URINE - POLYURIA
If the daily volume of urine increases above 3000 ml it is called polyuria. It is because of kidney's inability to concentrate the urine as a result of chronic nephiritis, diabetes and some times because of the use of diuretics.

(26) NOCTURIA - PASSING MORE URINE IN NIGHT
When more urine is passed during night disturbing one's sleep, than the day time, It is
known as nocturia. It may be symptom of diabetes, congestive cardiac failure or chronic renal insufficiency.
(m) Feeling of pain from excretory organs. The pain in the kidney will be a dull one, felt in loin and lumbar regions. Various pains in the pubic area, in the root of the penis and generally in the lower abdomen may be indication of the diseases of bladder, prostate glands, uretheral infections.


(27) PASSING BLOOD IN URINE
The presence of blood in urine (Haematuria) may be due to glomerulonephritis or some
bleeding disorders or stones or tumours. If you collect urine in three glasses in the beginning, middle and end of the urination you can locate the site of bleeding. In glomerulonephritis the urine is uniformly blood stained. Reddish colour of urine need not mean blood in urine it may be due to several substances, clinical test will give the proper result.
(a) Pus, blood or crystals will make urine turbid.
(b) The presence of gas in urine may be due to urinary track infection of bladder by gas
forming organisms.
(c) The fluid retention or edema is the symptom of acute glomerulonephritis and
nephrotic syndrome. There is puffiness of the eyelids and face especially on walking from
sleep. In scrotum and breast also edema will be seen.
(d) Fever is a prominent symptom. In certain cases fever will be intermitent In chronic cases fever may prominent Tumours in the kidney may give rise to irregular fever.

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