KASINI
PLUS FOR DIABETES
Kasini Plus, a coded herbal preparation has various
medicinal effects, and medicinal values, including anti infalmmatory,
antidiabetic, antihypertensive and antilipidemic effects.
A project was undertaken by Department of Bio-Chemistry, Avinashilingam
University, Coimbatore, to analyze the nutritional and bio-chemical
constituents of the Kasini Plus and correlate their levels with
medicinal properties.
Analysis of Kasini Plus showed that it contains phytochemicals
like carbohydrates, protein, polyphenols, tannins, flavonoids,
alkaloids and saponins., It is also a rich source of minerals
and antioxidants, catalase, peroxidase, and SOD ascorbic acid,
tocopherol, 22-carotene, riboflavin, polyphenols, flavonoids
and tannins.
Kasini Plus has reasonably good amounts of minerals such as
calcium, phosphorous, and iron.
Inhibition of in vitro lipid peroxidation by the extracts of
Kasini Plus showed that it effectively neutralizes the free
radicals and thus prevents lipid peroxidation.
Kasini Plus did not induce and mutation in the strains TA98,
TA102. It is anti mutagenic and anti carcinogenic. Kasini Plus
has brought down the elevated blood glucose and lipid levels
in the alloxan induced diabetic rats. This suggested that it
is hypoglycemic and hypolipidemic. The antioxidant levels in
the rats also proved that it has protection against free radical
damage. It is also non toxic. Thus this investigation very well
establishes the antidiabetic effect of Kasini Plus and also
its potency in preventing the complications of the diabetes
mellitus.